WHO publishes clinical management guidelines for filovirus disease (Ebola, Marburg, Sudan, Bundibugyo, Taï Forest) (who.int)

• WHO released harmonized clinical management guidelines covering all filoviruses pathogenic to humans (Ebola, Sudan, Bundibugyo, Taï Forest, Marburg).
• Recommendations include systematic monitoring, fluid therapy, shock management, vasopressors, bacterial co-infection treatment, haemorrhagic complication management, and survivor follow-up.
• Developed using GRADE methodology and evidence-to-decision frameworks, targeting resource-constrained outbreak settings.

"The World Health Organization released evidence-based guidelines for the clinical management of filovirus disease, covering Ebola, Sudan, Bundibugyo, Taï Forest, and Marburg viruses. Developed using GRADE methodology, the 86-page document harmonizes previous disease-specific guidance and provides recommendations for systematic clinical and laboratory monitoring, fluid therapy, shock management, vasopressor use, bacterial co-infection treatment, hemorrhagic complication management, and post-discharge follow-up. Aimed at clinicians in resource-constrained settings, the guideline emphasizes patient-centred supportive care integrated with infection prevention and control measures to improve outcomes during outbreaks."