WHO Guidelines for Clinical Management of Filovirus Disease (2026) (iris.who.int)

• First WHO guideline to cover all filoviruses (Ebola, Marburg, Sudan, etc.) using GRADE methodology.
• Provides evidence-based recommendations on fluid management, vasopressors, co-infection treatment, and hemorrhagic disease management.
• Includes specific guidance on post-discharge follow-up and PPE use by survivors.

"The World Health Organization has released comprehensive clinical management guidelines for filovirus disease, covering Ebola, Marburg, Sudan, Bundibugyo, and Taï Forest viruses. Developed using GRADE methodology and systematic evidence reviews, the guidelines expand beyond previous Ebola-specific guidance to harmonize approaches across all filoviruses. Key recommendations address fluid therapy, vasopressor use, management of hemorrhagic disease, treatment of co-infections, post-discharge follow-up, and personal protective equipment for survivors working in treatment centers. The document provides a standardized framework for clinicians in outbreak settings."