Bundibugyo virus: Rare Ebola species with no approved vaccines or therapeutics (scientificamerican.com)

• Outbreak with >130 deaths and >500 infections in DRC and Uganda
• WHO declared PHEIC on May 17, 2026
• No approved vaccines or therapeutics for Bundibugyo
• CFR 30-50%, >30% genetically distinct from other Ebola viruses

"The Bundibugyo virus, a rare orthoebolavirus species, has caused an outbreak in DRC and Uganda with over 130 deaths and 500 infections. WHO declared it a PHEIC on May 17, 2026. Unlike the better-known Ebola virus (Zaire), no approved vaccines or monoclonal antibodies exist for Bundibugyo. CFR is 30-50%. The virus is over 30% genetically distinct, making existing vaccines unlikely to protect."