CDC Clinical Guidance for Ebola Bundibugyo Virus: Outbreak Overview and Recommendations for Clinicians (May 2026) (cdc.gov)

• 1,077 suspected, 121 confirmed cases in DRC as of May 23, 2026
• No licensed treatment; experimental MBP134 shows efficacy in non-human primates
• CDC advises travel history, malaria testing, and strict infection control for suspected cases

"This CDC COCA call from May 28, 2026, provides clinicians with an overview of the ongoing Bundibugyo virus (BVD) outbreak in DRC and Uganda. As of May 23, DRC reported 1,077 suspected cases, 121 confirmed cases, 246 suspected deaths, and 17 confirmed deaths; Uganda reported 7 confirmed cases and 1 death. The virus is primarily transmitted through direct contact with body fluids. No FDA-licensed treatment exists for BVD; experimental antibody cocktail MBP134 has shown efficacy in non-human primates. The Ervebo vaccine is unlikely to provide cross-protection. Clinicians are advised to take travel history, rule out malaria, and implement strict infection control when suspecting Ebola."