Ebola Vaccines Exist, But Not for Bundibugyo Strain in Current Uganda Outbreak (scientificamerican.com)

• FDA-approved Ebola vaccines only target Zaire ebolavirus, not Bundibugyo.
• Current outbreak in Uganda has >100 cases with high CFR.
• CEPI funds multivalent vaccine research but regulatory barriers remain.

"Scientific American reports that while licensed Ebola vaccines (Ervebo, Zabdeno/Mvabea) target Zaire ebolavirus, no approved vaccine exists for the Bundibugyo strain responsible for the current outbreak in Uganda. This gap underscores the need for multivalent vaccines and rapid response platforms. The article discusses challenges of strain-specific immunity and ongoing research into broad-spectrum filovirus vaccines."