Ebola Outbreak 2026 in DRC and Uganda: Virus Biology, Vaccine Gaps, and Treatment Options (nam.edu)

• Outbreak in DRC and Uganda with Bundibugyo strain.
• No specific vaccines or treatments for Bundibugyo.
• Existing vaccines (Ervebo, Zabdeno/Mvabea) only for Zaire strain.
• Monoclonal antibodies Inmazeb and Ebanga only for Zaire.
• WHO report: ~600 suspected cases, 139 deaths as of May 20, 2026.

"An interview with Dr. Carlos del Rio published by the National Academy of Medicine explains Ebola basics, transmission, symptoms, and why current vaccines and treatments (Inmazeb, Ebanga) only work against the Zaire strain. The current outbreak in DRC and Uganda is caused by the rare Bundibugyo strain, which has high fatality and no specific vaccines or treatments. As of May 20, 2026, WHO reported approximately 600 suspected cases, 139 deaths, 51 confirmed in DRC, and 2 imported cases in Uganda."