Safety, Tolerability, Pharmacokinetics, and Immunogenicity of mAb114 (pmc.ncbi.nlm.nih.gov)
0xBASE INTEL BRIEF
- Phase 1 trial shows favorable safety profile.
- Neutralizes Zaire Ebola strain.
- Derived from survivor antibodies.
- Supports single-dose regimen.
"This article details a clinical study on mAb114, a monoclonal antibody candidate for Ebola virus disease. It covers safety, tolerability, pharmacokinetics, and immunogenicity data from Phase 1 trials, supporting its potential as a therapeutic. The findings are crucial for the medical countermeasure pipeline."
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