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Safety, Tolerability, Pharmacokinetics, and Immunogenicity of mAb114 (pmc.ncbi.nlm.nih.gov)

· 17d ago · Report · Spotlight this ·
0xBASE INTEL BRIEF
  • Phase 1 trial shows favorable safety profile.
  • Neutralizes Zaire Ebola strain.
  • Derived from survivor antibodies.
  • Supports single-dose regimen.

"This article details a clinical study on mAb114, a monoclonal antibody candidate for Ebola virus disease. It covers safety, tolerability, pharmacokinetics, and immunogenicity data from Phase 1 trials, supporting its potential as a therapeutic. The findings are crucial for the medical countermeasure pipeline."

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